![]() Table S3: Receiver operating characteristic derived cut-off values for the TTE PH parameters. Table S2: Comparison of echocardiographic markers of RV diastolic dysfunction in those with and without PH. Table S1: Population characteristics (N = 310). RV TDI IVRT (right ventricular tissue Doppler imaging isovolumetric relaxation times). Figure S5b: Comparison of average RV TDI IVRT values (ms) in those with intermediate TTE probability in those with PH (N = 27) and without N = 13). Figure S5a: Comparison of average RV TDI IVRT values (ms) in those with low TTE probability with PH (N = 17) and without (N = 28). However, IVRT values were significantly higher in those with PAH (P < 0.001) and CTEPH (P < 0.01) compared to those without PH (H = 24.3(5) P < 0.001). Kruskal–Wallis analysis demonstrated IVRT values were not statistically significantly different across WHO classifications of PH. Figure S4c: Comparison of RV TDI IVRT (ms) relative to WHO classifications of PH. Kruskal–Wallis analysis demonstrated E/A ratios were significantly different across WHO classifications of PH H = 33.1(5), P 0.05). Figure S4b: Comparison of RV TDI E’:A’ ratios relative to WHO classifications of PH. Kruskal–Wallis analysis demonstrated RV TDI e’ values were different across WHO classifications of PH H = 31.7(5) P 0.05). Figure S4a: Comparison of RV TDI e’ (cm/s) relative to WHO classifications of PH. RVFWLS values however were significantly higher in those without PH compared to all WHO classifications of PH, H = 31.12 (5) (all P 73 ms demonstrated sensitivity and specificity of 81% and 62%, respectively for detecting PH. Kruskal–Wallis analysis showed no statistically significant difference in RVFWLS values relative to WHO classification in either group (p > 0.05). Figure S1b: Comparison of RVFWLS values relative to WHO classification of PH. Kruskal–Wallis analysis demonstrated RVFWLS was significantly different relative to TTE PH probability group H = 51.73 (3) (P 0.05). The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.Īdditional file 1: Figure S1a: Comparison of average RV free wall longitudinal strain (RVFWLS) in those with a high, intermediate or low TTE probability as well as those without PH. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
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